GeoJSON, a widely used format based on JSON (JavaScript Object Notation), is specifically designed for encoding a variety of geographic data structures. This versatile format excels in representing simple geographical features, such as points, lines, and polygons, along with their non-spatial attributes. In the realm of digital pathology, GeoJSON has emerged as a common format for storing annotations, enabling precise documentation of regions of interest, cellular structures, and other critical details within pathology images. The popularity of GeoJSON in this field is bolstered by its broad support across numerous tools (e.g., Qupath) and thus facilitates seamless integration and analysis in digital pathology workflows.

Despite its widespread adoption, there are several open questions regarding the efficient use of GeoJSON that can significantly impact performance. One key concern is the best method for storing GeoJSON in a compressed format to minimize storage requirements while preserving the integrity of the data. Efficient compression techniques are crucial, especially when dealing with large-scale pathology datasets.